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Cat. No.: HY-117555

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4010B-30

Name: 4010B-30
Brand: MedChemExpress
SKU: HY-117555
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4010B-30 is a upregulator of apolipoprotein A-I (ApoA-I). 4010B-30 regulates ApoA-I gene expression through activation of PPARγ. 4010B-30 promotes cholesterol efflux and ABCA1 expression. 4010B-30 protects against atherosclerotic lesion development in ApoE^-/- mice.

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CAS No.: 1415477-76-7
Formule: C₁₇H₂₀F₄N₂O
Masse moléculaire:344.35

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

4010B-30 Chemical Structure

CAS No.: 1415477-76-7

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Chemical Information

CAS No. 1415477-76-7
Masse moléculaire 344.35
Formule C₁₇H₂₀F₄N₂O
SMILES

O=C(C1=CC=C(F)C(C(F)(F)F)=C1)N2CC3(CCN(C)CC3)CC2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Du Y, et al. A novel compound 4010B-30 upregulates apolipoprotein A-I gene expression through activation of PPARγ in HepG2 cells. Atherosclerosis. 2015 Apr;239(2):589-98. [Content Brief]

[2]. Hong, Bin et al. Effects of 4010B-30, A novel small molecule, on the endogenous apolipoprotein A-I expression and the development of atherosclerosis. Atherosclerosis, Volume 263, e74

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4010B-30

Voir tous les produits spécifiques à Isoform Apolipoprotein

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