A-1208746
A-1208746 is an inhibitor for MCL-1, with a Ki of 0.454 nM. A-1208746 activates caspase-3/-7, induces apoptosis in cell H929, and decreases mitochondrial membrane potential. A-1208746 synergies with Navitoclax (HY-10087), and can be used in cancer research.
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- CAS No.: 1668553-23-8
- Formule: C45H52N6O7S
- Masse moléculaire:821.00
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Ki: 0.454 nM (MCL-1)
Chemical Information
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CAS No. 1668553-23-8
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Masse moléculaire 821.00
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Formule C45H52N6O7S
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SMILES
O=S(N(CC1)CCN1C2=CC=C(OCC3=C(C4=C(N(CCN5CCOCC5)C(C(O)=O)=C6CCCOC7=C(C=CC=C8)C8=CC=C7)C6=CC=C4)C(C)=NN3C)C=C2)(C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)