Ceftezole
Ceftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity.
At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Ceftezole sodium) usually boasts enhanced water solubility and stability.
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- CAS No.: 26973-24-0
- Formule: C13H12N8O4S3
- Masse moléculaire:440.48
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
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β-lactam |
In Vitro
Ceftezole is a broad-spectrum antibiotic, active in vitro against many species of gram-positive and gram-negative bacteria except, Serratia marcescens and Proteus vulgaris[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 26973-24-0
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Masse moléculaire 440.48
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Formule C13H12N8O4S3
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SMILES
O=C(C(N12)=C(CSC3=NN=CS3)CS[C@]2([H])[C@H](NC(CN4N=NN=C4)=O)C1=O)O
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Synonyms
CTZ
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20(3):379-83. [Content Brief]
[2]. Harada Y, et al. Ceftezole, a new cephalosporin C derivative II. Distribution and excretion in parenteral administration. J Antibiot (Tokyo). 1976 Oct;29(10):1071-82. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)