HL389
HL389 inhibits proliferation of cancer cells MDA-MB-231 and MCF-7, with IC50 of 11.39 μM and 9.66 μM. HL389 can be utilized as the ligand for E3 ligase for the synthesis of PROTAC degrader HL435 (HY-161769).
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- Formule: C22H19BrF3NO4
- Masse moléculaire:498.29
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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Cereblon |
DCAF11 |
Chemical Information
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Masse moléculaire 498.29
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Formule C22H19BrF3NO4
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SMILES
BrC(C=C1)=CC(/C=C(C(C=CC(C(F)(F)F)=C2)=C2N3)\C3=O)=C1OCC(OC(C)(C)C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)