INDOPY-1
INDOPY-1 (Indolopyridone-1) is a selective, reversible, and competitive HIV-1 reverse transcriptase inhibitor. INDOPY-1 reversibly binds to the active site of reverse transcriptase. INDOPY-1 inhibits DNA synthesis. INDOPY-1 exhibits antiviral activity against various retroviruses, including HIV-1 IIIB, HIV-1 HXB2 K103N Y181C, HIV-2 ROD, and SIV Mac251. INDOPY-1 can be used in the research of immunodeficiency virus infection.
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- CAS No.: 352548-47-1
- Formule: C19H12N4O3
- Masse moléculaire:344.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
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HIV-1 |
HIV-2 |
INDOPY-1 inhibits DNA synthesis, with an IC50 of 0.29 μM measured using Poly (rA) · poly (dT) and an IC50 of 1.1 μM measured using Poly (rI) · poly (dC)[1].
INDOPY-1 exhibits antiviral activity against diverse retroviruses, including HIV-1 IIIB, HIV-1 HXB2 K103N Y181C, HIV-2 ROD, and SIV Mac251[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 352548-47-1
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Masse moléculaire 344.32
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Formule C19H12N4O3
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SMILES
N#CC(C(N1C2=CC=C([N+]([O-])=O)C=C2)=O)=CC(N3C)=C1C4=C3C=CC=C4
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Synonyms
Indolopyridone-1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
INDOPY-1 Related Classifications
HY-182474 Related Classifications
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