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Cat. No.: HY-116279

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JG-48

JG-48 is a Hsp70 inhibitor that can reduce tau levels in models of tauopathy.

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CAS No.: 1627122-26-2
Formule: C₂₀H₁₆F₃N₃OS₂
Masse moléculaire:435.49

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

JG-48 Chemical Structure

CAS No.: 1627122-26-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

JG-48 is a Hsp70 inhibitor that can reduce tau levels in models of tauopathy^[1].

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Chemical Information

CAS No. 1627122-26-2
Masse moléculaire 435.49
Formule C₂₀H₁₆F₃N₃OS₂
SMILES

O=C1N(CC)/C(S/C1=C2SC3=CC(C(F)(F)F)=CC=C3N/2C)=C/C4=NC=CC=C4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Young ZT, et al. Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy. Cell Chem Biol. 2016 Aug 18;23(8):992-1001. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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JG-48

Voir tous les produits spécifiques à Isoform HSP

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

JG-48 Related Classifications

HY-116279 Related Classifications

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