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Cat. No.: HY-174994

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JY-5

JY-5 is an E3 ligase ligand. JY-5 can be used for synthesis of PROTAC JY-21 (HY-174975).

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Formule: C₂₀H₂₇N₃O₃Si
Masse moléculaire:385.53

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

JY-5 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

JY-5 is an E3 ligase ligand. JY-5 can be used for synthesis of PROTAC JY-21 (HY-174975)^[1].

Voir tous les produits spécifiques à Isoform Ligands for E3 Ligase :

Chemical Information

Masse moléculaire 385.53
Formule C₂₀H₂₇N₃O₃Si
SMILES

CC(C)[Si](C(C)C)(C(C)C)C#C/N=N/C(C([N+]([O-])=O)=C1)=CC=C1OCC#C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Du J,et al. Azoacetylene Electrophiles for Proteome-wide Ligand and Target Discovery: Supporting Targeted Protein Degradation. J Med Chem. 2025 Jul 10;68(13):13516-13531. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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JY-5

Voir tous les produits spécifiques à Isoform Ligands for E3 Ligase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

JY-5 Related Classifications

HY-174994 Related Classifications