ML189
ML189 is an HSP90 inhibitor. ML189 can be used in the research of infectious diseases such as candidiasis.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 337328-21-9
- Formule: C20H17Cl2N3O
- Masse moléculaire:386.27
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
HSP90 |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
21 μM
Compound: 1, ML189
|
Cytotoxicity in mouse NIH/3T3 cells after 48 hrs by Almar blue fluorimetry
Cytotoxicity in mouse NIH/3T3 cells after 48 hrs by Almar blue fluorimetry
|
[PMID: 21802942] |
Chemical Information
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CAS No. 337328-21-9
-
Masse moléculaire 386.27
-
Formule C20H17Cl2N3O
-
SMILES
O=C(C1=CC=C(Cl)C=C1)N2CCN(C3=CC=NC4=CC(Cl)=CC=C34)CC2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Hartland CL, et al. Identification of small molecules that selectively inhibit fluconazole-resistant Candida albicans in the presence of fluconazole but not in its absence. 2010 Oct 29. [Content Brief]
[2]. Tian J, et al. Overcoming matrix effects: GC method development for the determination of triethylamine and dimethyl sulfoxide in a drug substance. J Chromatogr Sci. 2014 Jan;52(1):36-41. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)