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Cat. No.: HY-103404

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PNU-96415E

PNU-96415E is a selective D₄/5-HT_2A antagonist. PNU-96415E may have potential antipsychotic efficacy.

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CAS No.: 170856-41-4
Formule: C₂₁H₂₇Cl₂FN₂O
Masse moléculaire:413.36

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PNU-96415E Chemical Structure

CAS No.: 170856-41-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

PNU-96415E is a selective D₄/5-HT_2A antagonist. PNU-96415E may have potential antipsychotic efficacy^[1].

IC₅₀ & Target^[1]

D₄ Receptor

5-HT_2A Receptor

Voir tous les produits spécifiques à Isoform Dopamine Receptor :

Voir tous les produits spécifiques à Isoform 5-HT Receptor :

In Vivo

PNU-96415E blockes 5-HTP-induced bead twitches in mice and stereotypic behaviours produced by high doses of amphetamine and methylphenidate^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 170856-41-4
Masse moléculaire 413.36
Formule C₂₁H₂₇Cl₂FN₂O
SMILES

FC1=CC=C(N2CCN(CCC3C4=CC=CC=C4CCO3)CC2)C=C1.[H]Cl.[H]Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Kulkarni SK, et al. Dopamine D4 receptors and development of newer antipsychotic drugs. Fundam Clin Pharmacol. 2000;14(6):529-539. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureté et documentation
Références

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PNU-96415E

Voir tous les produits spécifiques à Isoform Dopamine Receptor

Voir tous les produits spécifiques à Isoform 5-HT Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

PNU-96415E Related Classifications

HY-103404 Related Classifications