PRMT5-IN-21
PRMT5-IN-21 (compound 1) is a potent cyclonucleoside PRMT5 inhibitor.
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- CAS No.: 2922673-38-7
- Formule: C18H18F2N6O3
- Masse moléculaire:404.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform Histone Methyltransferase
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Activité biologique
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PRMT5 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf21 | IC50 |
5.7 μM
Compound: 1
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Inhibition of full-length (FL)-PRMT5:MEP50 enzyme complex (unknown origin) expressed in Sf21 cells assessed as reduction in methylation activity using the N-terminus of H4 histone derived substrate peptide H4R3(Me1) by PRMT5:MEP50 biochemical assay
Inhibition of full-length (FL)-PRMT5:MEP50 enzyme complex (unknown origin) expressed in Sf21 cells assessed as reduction in methylation activity using the N-terminus of H4 histone derived substrate peptide H4R3(Me1) by PRMT5:MEP50 biochemical assay
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[PMID: 35594650] |
Chemical Information
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CAS No. 2922673-38-7
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Masse moléculaire 404.37
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Formule C18H18F2N6O3
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SMILES
FC1=C(F)C=CC([C@@H]2[C@@H]3[C@@H](O)[C@@H](O)[C@H](N4C(N=CN=C5N)=C5N=C4NCC2)O3)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PRMT5-IN-21 Related Classifications
HY-150081 Related Classifications
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