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Tilrekimig

(Synonyms: PF-07275315)
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Based on 1 Customer Validation

Tilrekimig (PF-07275315) is a monoclonal antibody targeting human interleukin-4 (IL-4), interleukin-13 (IL-13) and thymic stromal lymphopoietin (TSLP). Tilrekimig can be used in the research of allergic and inflammatory diseases, such as asthma and atopic dermatitis.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

  • Pureté : 97.00%
  • CAS No.: 2981469-90-1
  • Masse moléculaire:193.681 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tilrekimig
  • Experimental Validation Results for Tilrekimig
  • Experimental Validation Results for Tilrekimig
  • Experimental Validation Results for Tilrekimig
  • Experimental Validation Results for Tilrekimig
  • Experimental Validation Results for Tilrekimig
  • Tilrekimig Chemical Structure
    Tilrekimig Chemical Structure
CAS No.: 2981469-90-1
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Tilrekimig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Fab-kappa_IgG1-kappa-lambda_disulfide

  • 1/16

    Loaded Tilrekimig on ProA biosensor, can bind HY-P70764 IL-4 Protein, Human (HEK293, His) with an affinity constant of 3.074E-10 M as determined in BLI assay.

  • 1/16

    Loaded Tilrekimig on ProA biosensor, can bind HY-P70568 IL-13 Protein, Human (HEK293, His) with an affinity constant of 1.917E-09 M as determined in BLI assay.

  • 1/16

    Loaded Tilrekimig on ProA biosensor, can bind HY-P70818 TSLP Protein, Human (HEK293, His) with an affinity constant of 1.060E-09 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 Ramos cells labeling IL-4 with Tilrekimig (HY-P991162, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells labeling TSLP with Tilrekimig (HY-P991162, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Tilrekimig Chemical Structure
    1/16
  • Tilrekimig
  • Loaded Tilrekimig on ProA biosensor, can bind HY-P70764 IL-4 Protein, Human (HEK293, His) with an affinity constant of 3.074E-10 M as determined in BLI assay.
  • Loaded Tilrekimig on ProA biosensor, can bind HY-P70568 IL-13 Protein, Human (HEK293, His) with an affinity constant of 1.917E-09 M as determined in BLI assay.
  • Loaded Tilrekimig on ProA biosensor, can bind HY-P70818 TSLP Protein, Human (HEK293, His) with an affinity constant of 1.060E-09 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 Ramos cells labeling IL-4 with Tilrekimig (HY-P991162, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Flow cytometric analysis of 1X106 Jurkat cells labeling TSLP with Tilrekimig (HY-P991162, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Fab-kappa_IgG1-kappa-lambda_disulfide