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Cat. No.: HY-158047

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UNC8900

UNC8900 is a VHL recruiting STING PROTAC degrader (DC₅₀: 0.0.924 μM). UNC8900 can be used for research of viral or bacterial infection. (Blue: VHL ligand, black: linker; Pink: STING inhibitor).

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 3094059-45-4
Formule: C₇₅H₉₉N₁₇O₁₅S
Masse moléculaire:1510.76

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

UNC8900 Chemical Structure

CAS No.: 3094059-45-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform PROTACs :

In Vitro

UNC8900 (3 μM, 8 h) induces STING protein expression in HKC-8 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3094059-45-4
Masse moléculaire 1510.76
Formule C₇₅H₉₉N₁₇O₁₅S
SMILES

O=C(C1=CC2=C(N(C(NC(C3=CC(C)=NN3CC)=O)=N2)C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=C4C(OCCCN7CCOCC7)=CC(C(N)=O)=C6)C(OC)=C1)NCCOCCOCCOCCOCCC(N[C@H](C(C)(C)C)C(N8[C@@H](C[C@@H](O)C8)C(NCC9=CC=C(C%10=C(N=CS%10)C)C=C9)=O)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhu Z, et al. Development of VHL-recruiting STING PROTACs that suppress innate immunity. Cell Mol Life Sci. 2023 May 14;80(6):149. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références

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UNC8900

Voir tous les produits spécifiques à Isoform PROTACs

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

UNC8900 Related Classifications

HY-158047 Related Classifications