Caylin-2
Based on 1 Customer Validation
Caylin-2 is a Bcl-XL binder and analog of Nutlin-3 (HY-50696). Caylin-2 interacts with the hydrophobic groove of Bcl-XL, with binding diminished by steric collision from its trifluoromethyl groups. Caylin-2 can be used for cancer research.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 99.0%
- CAS No.: 1392830-09-9
- Formule: C32H30F6N4O4
- Masse moléculaire:648.60
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Stockage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
Bcl-xL |
In Vitro
Caylin-2 binds to the conserved hydrophobic groove of purified Bcl-XL protein but induces substantially diminished chemical shift perturbations, indicating weaker binding than Nutlin-3[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1392830-09-9
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Appearance Solid
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Masse moléculaire 648.60
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Formule C32H30F6N4O4
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Color White to off-white
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SMILES
O=C(N1CC(NCC1)=O)N2[C@@H](C3=CC=C(C=C3)C(F)(F)F)[C@@H](C4=CC=C(C=C4)C(F)(F)F)N=C2C5=C(C=C(C=C5)OC)OC(C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureté et documentation
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Fiche technique (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Caylin-2 Related Classifications
HY-117585 Related Classifications
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