CB07-Exatecan
Based on 1 Customer Validation
CB07-Exatecan is an ADC drug-Linker conjugate that can be used for the synthesis of ADCs. ADC conjugated with CB07-Exatecan and trastuzumab inhibits the growth of HER2-positive cancer cells. CB07-Exatecan can be used in cancer research.
For research use only. We do not sell to patients.
- Purity: 98.97%
- CAS No.: 2879247-31-9
- Formula: C71H94FN11O22
- Molecular Weight:1472.56
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Camptothecins |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2879247-31-9
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Appearance Solid
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Molecular Weight 1472.56
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Formula C71H94FN11O22
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Color Light yellow to yellow
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SMILES
O=C(C=CC1=O)N1CC(N[C@@H](CCNC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (67.91 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.6791 mL | 3.3954 mL | 6.7909 mL | 16.9772 mL |
| 5 mM | 0.1358 mL | 0.6791 mL | 1.3582 mL | 3.3954 mL | |
| 10 mM | 0.0679 mL | 0.3395 mL | 0.6791 mL | 1.6977 mL | |
| 15 mM | 0.0453 mL | 0.2264 mL | 0.4527 mL | 1.1318 mL | |
| 20 mM | 0.0340 mL | 0.1698 mL | 0.3395 mL | 0.8489 mL | |
| 25 mM | 0.0272 mL | 0.1358 mL | 0.2716 mL | 0.6791 mL | |
| 30 mM | 0.0226 mL | 0.1132 mL | 0.2264 mL | 0.5659 mL | |
| 40 mM | 0.0170 mL | 0.0849 mL | 0.1698 mL | 0.4244 mL | |
| 50 mM | 0.0136 mL | 0.0679 mL | 0.1358 mL | 0.3395 mL | |
| 60 mM | 0.0113 mL | 0.0566 mL | 0.1132 mL | 0.2830 mL |
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