Azaspirene
Azaspirene ((-)-Azaspirene) is an angiogenesis and Raf-1 activation inhibitor isolated from the fungus Neosartorya sp. Azaspirene inhibits vascular endothelial growth factor (VEGF)-induced human umbilical vein endothelial cell (HUVEC) migration and Raf-1 activation, but has no effect on the activation of kinase insert domain-containing receptor/fetal liver kinase 1 (VEGF receptor 2).
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- CAS. Nr.: 461644-34-8
- Formel: C21H23NO5
- Molecular Weight:369.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 461644-34-8
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Molecular Weight 369.41
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Formel C21H23NO5
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SMILES
O[C@@H]1[C@]2(C(N[C@@]1(O)CC3=CC=CC=C3)=O)OC(/C=C/C=C/CC)=C(C2=O)C
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Synonyms
(-)-Azaspirene
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Structure Classification
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Initial Source
Neosartorya sp.
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Azaspirene Related Classifications
HY-N15264 Related Classifications
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