CEP-6800
CEP-6800 is an inhibitor of PARP-1 with chemopotentiating ability. CEP-6800 attenuates irinotecan (HY-16562)- and Temozolomide (HY-17364)-induced poly(ADP-ribose) accumulation in LoVo as well as HT29 xenografts. CEP-6800 can suppress Calu-6 tumor growth. CEP-6800 can be studied in anti-cancer research.
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- CAS. Nr.: 609848-02-4
- Formel: C18H15N3O2
- Molecular Weight:305.33
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U-251 | IC50 |
18 nM
Compound: 2
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Inhibition of human recombinant PARP1 in U251MG cells by CometAssay
Inhibition of human recombinant PARP1 in U251MG cells by CometAssay
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[PMID: 17074482] |
Chemical Information
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CAS. Nr. 609848-02-4
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Molecular Weight 305.33
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Formel C18H15N3O2
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SMILES
O=C1NC(C2=C1C3=C(C4=C2CCC4)NC5=C3C=C(CN)C=C5)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CEP-6800 Related Classifications
HY-119992 Related Classifications
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