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Art. -Nr.: HY-N18420

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Citriniorl A

Citriniorl A is a SIRT1 enhancer with an EC₅₀ of 5.8 μM. Citriniorl A binds to key amino acid residues in the SIRT1 active site to stabilize binding and enhance SIRT1-mediated deacetylation. Citriniorl A can be used for the research of metabolic disorders.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₁₄H₁₄O₄
Molecular Weight:246.26

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Citriniorl A Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle Sirtuin Isoform-spezifische Produkte anzeigen :

In Vitro

Citriniorl A (compound 1) (varying concentrations; 30 min pre-incubation, 1 h enzymatic reaction at 37°C) exhibits moderate SIRT1 activation activity with an EC₅₀ of 5.8 μM via stable binding to the SIRT1 active site^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 246.26
Formel C₁₄H₁₄O₄
SMILES

OC1=C(C)C([C@H](C)[C@@H](C)O2)=C(C2=CC(O3)=O)C3=C1
Structure Classification
- Phenylpropanoids
- Coumarins
- Others
Initial Source
- Microorganisms
Penicillium citrinum TJ507
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Zhang Y, et al. Discovery of citrinin derivatives with SIRT1 agonist activity from Penicillium citrinum TJ507. Bioorg Chem. 2026;170:109473. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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Citriniorl A

Alle Sirtuin Isoform-spezifische Produkte anzeigen