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Art. -Nr.: HY-N9647

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Dalbinol

Dalbinol is a rotenoid compound. Dalbinol can inhibit Wnt/β-catenin signaling pathway and promote β-catenin degradation. Dalbinol inhibits tumor cells proliferation and induces apoptosis. Dalbinol has antitumor activity.

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CAS. Nr.: 41993-79-7
Formel: C₂₃H₂₂O₈
Molecular Weight:426.42

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Dalbinol Chemical Structure

CAS. Nr.: 41993-79-7

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle Wnt Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	ED₅₀	<0.001 μg/mL Compound: 6	Cytotoxicity against human A549 cells Cytotoxicity against human A549 cells	[PMID: 8326318]
HCT-8	ED₅₀	<0.001 μg/mL Compound: 6	Cytotoxicity against human HCT8 cells Cytotoxicity against human HCT8 cells	[PMID: 8326318]
KB	ED₅₀	<0.001 μg/mL Compound: 6	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 8326318]
L5178Y	IC₅₀	0.2 μM Compound: 31	Cytotoxicity against mouse L5178Y cells by MTT assay Cytotoxicity against mouse L5178Y cells by MTT assay	[PMID: 28075580]
LNCaP	ED₅₀	5.4 μg/mL Compound: 8	Cytotoxicity against human LNCAP cells Cytotoxicity against human LNCAP cells	[PMID: 17125241]
Lu1	ED₅₀	3.1 μg/mL Compound: 8	Cytotoxicity against human Lu1 cells Cytotoxicity against human Lu1 cells	[PMID: 17125241]
MCF7	ED₅₀	13.1 μg/mL Compound: 8	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 17125241]
P388	ED₅₀	<0.001 μg/mL Compound: 6	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 8326318]
RPMI-7951	ED₅₀	<0.001 μg/mL Compound: 6	Cytotoxicity against human RPMI7951 cells Cytotoxicity against human RPMI7951 cells	[PMID: 8326318]
TE-671	ED₅₀	<0.001 μg/mL Compound: 6	Cytotoxicity against human TE671 cells Cytotoxicity against human TE671 cells	[PMID: 8326318]

Chemical Information

CAS. Nr. 41993-79-7
Molecular Weight 426.42
Formel C₂₃H₂₂O₈
SMILES

O[C@]12C3=CC(OC)=C(OC)C=C3OC[C@@]1([H])OC4=C(C[C@@H](O5)C(CO)=C)C5=CC=C4C2=O
Structure Classification
- Flavonoids
- Other Flavonoids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Zhu X, et al. Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cells. Oncotarget. 2017 Jul 18;8(29):47755-47766. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Dalbinol

Alle Wnt Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Dalbinol Related Classifications

HY-N9647 Related Classifications