DB07006
DB07006 (compound 18) is a potent, ATP-cpmpetitive dual inhibitor of Wee1 (IC50 = 0.030 μM) and Chk1 checkpoint kinases (IC50 = 0.018 μM). DB07006 demonstrates effective abrogation of the G2/M checkpoint in combination with DNA-damaging agents in cellular models. DB07006 can be used for cancer research.
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- CAS. Nr.: 622855-60-1
- Formel: C24H20N2O5
- Molecular Weight:416.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Chk1 0.018 μM (IC50) |
Wee1 0.030 μM (IC50) |
Chemical Information
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CAS. Nr. 622855-60-1
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Molecular Weight 416.43
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Formel C24H20N2O5
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SMILES
O=C1NC(C2=C(C3=C(N4CCCO)C=CC(O)=C3)C4=CC(C5=C(OC)C=CC=C5)=C21)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DB07006 Related Classifications
HY-160948 Related Classifications
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