EAAT2 activator 2
EAAT2 activator 2 (Compound 4(SF-2)) is a brain-penetrant excitatory amino acid transporter 2 (EAAT2) modulator (Ki=28.7 nM). EAAT2 activator 2 enhances EAAT2-mediated glutamate uptake, improving synaptic glutamate clearance. EAAT2 activator 2 is promising for research of neurodegenerative diseases (e.g., ALS, Alzheimer’s disease) .
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C20H22FN3O3
- Molecular Weight:371.41
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
|
EAAT2 28.7 nM (Ki) |
Chemical Information
-
Molecular Weight 371.41
-
Formel C20H22FN3O3
-
SMILES
FCCOC1=CC=C(C=C1)NC(C(N2CCN(CC2)C3=CC=CC=C3)=O)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)