JOSD2-IN-1
JOSD2-IN-1 (Compound 31) is a covalent JOSD2 inhibitor with an IC50 value of 1.95 μM. JOSD2-IN-1 inhibits JOSD2, thereby down-regulating KRAS expression. JOSD2-IN-1 exhibits significant anti-proliferative activity against HCT116 cells. JOSD2-IN-1 can be used for research on colorectal cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C27H32N6O2
- Molecular Weight:472.58
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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K-RAS |
Chemical Information
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Molecular Weight 472.58
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Formel C27H32N6O2
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SMILES
O=C(C1=C2NC(NC([C@@H]3[C@@]4([H])CN(C#N)C[C@@]34[H])=O)=NC2=CC=C1)NC56CC7(C)CC(C6)(C)CC(C7)C5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)