Progesterone-13C2
Based on 1 Customer Validation
Progesterone-13C2 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.7%
- CAS. Nr.: 82938-07-6
- Formel: C1913C2H30O2
- Molecular Weight:316.45
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 82938-07-6
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Unlabeled Cas 57-83-0
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Appearance Solid
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Molecular Weight 316.45
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Formel C1913C2H30O2
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Color White to off-white
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SMILES
CC([C@H]1CC[C@@]2([H])[C@]3([H])CCC4=[13CH][13C](CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O
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Synonyms
Pregn-4-ene-3,20-dione-13C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 50 mg/mL (158.00 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16. [Content Brief]
[3]. Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217(3):369-78. [Content Brief]
[4]. Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4(2):144-50. [Content Brief]
[5]. Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148(11):5433-41. Epub 2007 Aug 9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1601 mL | 15.8003 mL | 31.6006 mL | 79.0014 mL |
| 5 mM | 0.6320 mL | 3.1601 mL | 6.3201 mL | 15.8003 mL | |
| 10 mM | 0.3160 mL | 1.5800 mL | 3.1601 mL | 7.9001 mL | |
| 15 mM | 0.2107 mL | 1.0534 mL | 2.1067 mL | 5.2668 mL | |
| 20 mM | 0.1580 mL | 0.7900 mL | 1.5800 mL | 3.9501 mL | |
| 25 mM | 0.1264 mL | 0.6320 mL | 1.2640 mL | 3.1601 mL | |
| 30 mM | 0.1053 mL | 0.5267 mL | 1.0534 mL | 2.6334 mL | |
| 40 mM | 0.0790 mL | 0.3950 mL | 0.7900 mL | 1.9750 mL | |
| 50 mM | 0.0632 mL | 0.3160 mL | 0.6320 mL | 1.5800 mL | |
| 60 mM | 0.0527 mL | 0.2633 mL | 0.5267 mL | 1.3167 mL | |
| 80 mM | 0.0395 mL | 0.1975 mL | 0.3950 mL | 0.9875 mL | |
| 100 mM | 0.0316 mL | 0.1580 mL | 0.3160 mL | 0.7900 mL |
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