TrkB
TrkB, encoded by the NTRK2 gene, is the receptor tyrosine kinase for brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5. It is broadly expressed in the central nervous system, where BDNF/TrkB signaling strengthens synaptic plasticity, dendritic growth, and long-term potentiation, processes central to learning and memory. In the hypothalamus the same receptor participates in the regulation of appetite and body weight. TrkB signaling through SHC, PLC-gamma, and PI3K cascades also supports neuronal survival, and altered TrkB signaling has been linked to depression and to the response to antidepressant treatment, while oncogenic NTRK2 fusions occur in a subset of tumors.
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TrkB Recombinant Proteins (13)
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- 1
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
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