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Art. -Nr.: HY-117610

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Ro 31-8830

(Synonyms: Ro 32-0432 free base; Bisindolylmaleimide XI)

3 Cited Publications

Kundenbewertung

Based on 3 publication(s) in Google Scholar

Ro 31-8830 is an orally active, potent and selective inhibitor of protein kinase C with anti-inflammatory activity. Ro 31-8830 is promising for research of inflammatory disorders.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 131848-98-1
Formel: C₂₈H₂₈N₄O₂
Molecular Weight:452.55

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Ro 31-8830 Chemical Structure

CAS. Nr.: 131848-98-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

Ro 31-8830 is an orally active, potent and selective inhibitor of protein kinase C with anti-inflammatory activity. Ro 31-8830 is promising for research of inflammatory disorders^[1].

Alle PKC Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 131848-98-1
Molecular Weight 452.55
Formel C₂₈H₂₈N₄O₂
SMILES

O=C(NC1=O)C(C2=C3CC(CCN3C4=C2C=CC=C4)CN(C)C)=C1C5=CN(C6=C5C=CC=C6)C
Synonyms

Ro 32-0432 free base; Bisindolylmaleimide XI
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

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J Adv Res

Paeonol protects against doxorubicin-induced cardiotoxicity by promoting Mfn2-mediated mitochondrial fusion through activating the PKCε-Stat3 pathway. [Abstract]

2023 May:47:151-162. PMID: 35842187
Cell Mol Biol Lett

IP3R1-mediated MAMs formation contributes to mechanical trauma-induced hepatic injury and the protective effect of melatonin. [Abstract]

2024 Feb 2;29(1):22. PMID: 38308199
Cell Rep

KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway. [Abstract]

2025 Apr 19;44(5):115595. PMID: 40253697

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Mulqueen MJ, et al. Oral, anti-inflammatory activity of a potent, selective, protein kinase C inhibitor. Agents Actions. 1992 Sep;37(1-2):85-9. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Ro 31-8830

3 Cited Publications

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Biologische Aktivität
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Chemical Information
Publications (3)
Reinheit & Dokumentation
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Ro 31-8830

Publications Citing Use of MedChemExpress (MCE) Ro 31-8830

Alle PKC Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (3)

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Ro 31-8830 Related Classifications

HY-117610 Related Classifications