Succinimide-15N
Based on 1 Customer Validation
Succinimide-15N is the 15N-labeled Succinimide (HY-41877). Succinimide is a modifying agent. Binding of Succinimide to the 5-HT7 receptor induces clathrin-mediated endocytosis. Succinimide-modified liposomes exhibit high cellular uptake. Succinimide can be used in the study of glioblastoma.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.0%
- CAS. Nr.: 32807-36-6
- Formel: C4H515NO2
- Molecular Weight:100.08
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
[3]|
5-HT7 Receptor |
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 32807-36-6
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Unlabeled CAS 123-56-8
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Appearance Solid
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Molecular Weight 100.08
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Formel C4H515NO2
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Color White to off-white
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SMILES
O=C1[15NH]C(CC1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (281 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Jiang Y, et al. Discovery of novel pyrrolidine-2,5-dione scaffold PICK1 PDZ inhibitors as anti-ischemic stroke agents. European journal of medicinal chemistry. 2026 Feb 05;303:118410. [Content Brief]
[2]. Tilekar K, et al. Synthesis and Biological Evaluation of Pyrazoline and Pyrrolidine-2,5-dione Hybrids as Potential Antitumor Agents. ChemMedChem. 2020 Oct 05;15(19):1813-1825. [Content Brief]
[3]. Lubitz LJ, et al. Elevated Cellular Uptake of Succinimide- and Glucose-Modified Liposomes for Blood-Brain Barrier Transfer and Glioblastoma Therapy. Biomedicines. 2024 Sep 20;12(9):2135. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Succinimide-15N Related Classifications
HY-41877S Related Classifications
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Keywords
- Succinimide-15N
- 32807-36-6
- Isotope-Labeled Compounds
- Biochemical Assay Reagents
- 5-HT Receptor
- Liposome
- Serotonin Receptor
- 5-hydroxytryptamine Receptor
- 5-HT7 receptor
- antiproliferative activity
- blood-brain barrier
- brain cancer
- clathrin-mediated endocytosis
- glioblastoma
- human U-87 MG glioblastoma cells
- liposomes
- murine brain endothelial cells
- pyrrolidine-2,5-dione
- Inhibitor
- inhibitor
- inhibit