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Cat. No.: HY-W660701

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Bamipine

Bamipine is a potent histamine H1-receptor antagonist. Bamipine exhibits moderate activity against Mycobacterium tuberculosis. Bamipine has a mild sedative effect.

For research use only. We do not sell to patients.

CAS No.: 4945-47-5
Formula: C₁₉H₂₄N₂
Molecular Weight:280.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Bamipine Chemical Structure

CAS No.: 4945-47-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Bamipine is a potent histamine H1-receptor antagonist. Bamipine exhibits moderate activity against Mycobacterium tuberculosis. Bamipine has a mild sedative effect^[1]^[2].

IC₅₀ & Target^[1]

H₁ Receptor

All Histamine Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	LC₅₀	64.08 μg/mL Compound: 2	Cytotoxicity against HEK293 cells after 72 hrs by MTT assay Cytotoxicity against HEK293 cells after 72 hrs by MTT assay	[PMID: 18977145]

Chemical Information

CAS No. 4945-47-5
Molecular Weight 280.41
Formula C₁₉H₂₄N₂
SMILES

CN1CCC(CC1)N(CC1=CC=CC=C1)C1=CC=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Weis R, et al. Antimycobacterial and H1-antihistaminic activity of 2-substituted piperidine derivatives. Bioorg Med Chem. 2008 Dec 15;16(24):10326-31. [Content Brief]

[2]. Kountourelli JE, Markopoulou CK. A simultaneous analysis by high performance liquid chromatography of bamipine combined with tricyclic antidepressants and/or antipsychotics in dosage forms. Journal of liquid chromatography. 1991 Sep 1;14(15):2969-77.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Bamipine

All Histamine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Bamipine Related Classifications

HY-W660701 Related Classifications