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NAD+

(Synonyms: β-DPN; β-NAD; β-Nicotinamide Adenine Dinucleotide)
51 Cited Publications
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Based on 51 publication(s) in Google Scholar

NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

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  • Pureté: 99.96%
  • CAS No.: 53-84-9
  • Formule: C21H27N7O14P2
  • Masse moléculaire:663.43
  • Stockage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • NAD+ Chemical Structure
    NAD+ Chemical Structure
  • Experimental Validation Results for NAD+
  • Experimental Validation Results for NAD+
  • Experimental Validation Results for NAD+
  • Experimental Validation Results for NAD+
  • Experimental Validation Results for NAD+
  • Experimental Validation Results for NAD+
  • Experimental Validation Results for NAD+
  • Experimental Validation Results for NAD+
CAS No.: 53-84-9
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  • NAD+ Chemical Structure
    NAD+ Chemical Structure
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    NAD+ purchased from MedChemExpress. Usage Cited in: Redox Biol. 2024 Feb:69:103030. [Abstract]

    Customer Validation
     LDH release assay showed the glioma cell death caused by SRT2183 (40 μmol/L) at 24 h was attenuated when the cells were pretreated 1 h with EX527 (200 μmol/L) or supplemented with exogenous NAD+ (2 mmol/L).

  • 1/16

    NAD+ purchased from MedChemExpress. Usage Cited in: Redox Biol. 2024 Feb:69:103030. [Abstract]

    Customer Validation
     The declines of cysteine induced by SRT2183 (40 μmol/L) at 24 h were both suppressed by pretreating the cells 1 h with EX527 or supplementing exogenous NAD+ (2 mmol/L).

  • 1/16

    NAD+ purchased from MedChemExpress. Usage Cited in: Redox Biol. 2024 Feb:69:103030. [Abstract]

    Customer Validation
     Western blotting revealed RSL3-induced downregulation of SLC7A11 and GPX4 was enhanced by FK866, but attenuated by exogenous NAD+ (2 mmol/L) supplement.

  • 1/16

    NAD+ purchased from MedChemExpress. Usage Cited in: Redox Biol. 2024 Feb:69:103030. [Abstract]

    Customer Validation
     Pretreatment with FK866 (500 μmol/L) or supplement of exogenous NAD+ at 2 mmol/L for 1 h prevented RSL3-induced upregulation of ATF3 in both cytoplasmic and nuclear fractions.

  • 1/16

    NAD+ purchased from MedChemExpress. Usage Cited in: Redox Biol. 2024 Feb:69:103030. [Abstract]

    Customer Validation
     Supplement of exogenous NAD+ at 1 mmol/L could inhibit ATF3 upregulation in the cells treated with FK866 (500 μmol/L) for 24 h, and this inhibition became more apparent by increasing NAD+ dosage to 2 mmol/L.

  • 1/16

    NAD+ purchased from MedChemExpress. Usage Cited in: Acta Pharmacol Sin. 2023 Oct;44(10):2125-2138. [Abstract]

    Customer Validation
     Western blotting proved supplement of exterior NAD+ (0.5-2 mmol/L, 1 h) dosage-dependently alleviated DPT-induced downregulation of phospho-AKT and upregulation of NOX2, NAT10, phospho-CREB, PARP1, and PAR.

  • 1/16

    NAD+ purchased from MedChemExpress. Usage Cited in: Vascul Pharmacol. 2022 Dec:147:107126. [Abstract]

    Customer Validation
     NAD+ significantly improves the expression of CD31 in the MI mice and DM + MI mice.

  • 1/16

    NAD+ purchased from MedChemExpress. Usage Cited in: Vascul Pharmacol. 2022 Dec:147:107126. [Abstract]

    Customer Validation
     NAD+ significantly improves the expression of VEGF in the MI mice and DM + MI mice.

  • NAD+