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Cat. No.: HY-179118

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Antimalarial agent 53

Antimalarial agent 53 (compound 31) is an antimalarial agent. Antimalarial agent 53 blocks protein synthesis by inhibiting the cytoplasmic ribosomes of malaria parasites, exhibiting potent antimalarial activity (IC₅₀ = 3.9 nM) and good selectivity. Antimalarial agent 53 has no cross resistance and good safety. Antimalarial agent 53 can be used for research on malaria.

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Formule: C₂₄H₂₄F₃N₅O₃
Masse moléculaire:487.47

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Antimalarial agent 53 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

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Chemical Information

Masse moléculaire 487.47
Formule C₂₄H₂₄F₃N₅O₃
SMILES

O=C(NC1=CC(NN2CCN(C)CC2)=CC=C1O)C3=CC(OC4=CC(C(F)(F)F)=CC=N4)=CC=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Bravo P, et al. A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum. Angew Chem Int Ed Engl. 2025 Oct 20:e202514085. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
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Antimalarial agent 53

Voir tous les produits spécifiques à Isoform Parasite

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Antimalarial agent 53 Related Classifications

HY-179118 Related Classifications