BRF110
BRF110 is the selective, orally active rexinoid for Nurr1-RXRα, that selectively activates the Nurr1-RXRα heterodimer with an EC50 of 0.9 μM in SH-SY5Y. BRF110 upregulates the expression of BDNF, exhibits neuroprotective activity against MPP+ induced toxicity. BRF110 can cross blood-brain barrier.
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- CAS No.: 2095489-35-1
- Formule: C22H18F3N3O2
- Masse moléculaire:413.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Activité biologique
Chemical Information
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CAS No. 2095489-35-1
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Masse moléculaire 413.39
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Formule C22H18F3N3O2
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SMILES
O=C(O)C1=CC=C(N(C)C2=NC(C3=CC=CC=C3)=NC(C(F)(F)F)=C2CC=C)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRF110 Related Classifications
HY-138967 Related Classifications
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