D-NAME

D-NAME (40 mg/kg/day; p.o.; daily; 4 weeks) inhibits myocardial NO synthase activity by 25% and aortic NO synthase activity by 13% in Rattus norvegicus, increasing systolic blood pressure by 27%, inducing a 13% increase in LVW/BW ratio, 25% increase in aortic wall mass, and elevating myocardial fibrosis to 5.25% of heart muscle area^[1].\n\nWait, correction: The original text uses "rats" which is the common name, not the Latin binomial. The correct formatting should retain "rats" as is, not convert to Latin. Here's the accurate version:\n\nD-NAME (40 mg/kg/day; p.o.; daily; 4 weeks) inhibits myocardial NO synthase activity by 25% and aortic NO synthase activity by 13% in rats, increasing systolic blood pressure by 27%, inducing a 13% increase in LVW/BW ratio, 25% increase in aortic wall mass, and elevating myocardial fibrosis to 5.25% of heart muscle area^[1].
D-NAME (50 mg/kg; i.p.; twice) does not inhibit OVA-induced pulmonary eosinophilia in sensitized male B6D2F1/J mice^[2].
D-NAME (222 μmol/kg; i.p.; daily; 4 days) pretreatment potentiates nitrodilator (BDNIC, NTG)-mediated mesenteric vasodilation, increases mean arterial blood pressure, and decreases baseline mesenteric arterial conductance in female Sprague-Dawley rats^[3].