EAAT2 activator 2
EAAT2 activator 2 (Compound 4(SF-2)) is a brain-penetrant excitatory amino acid transporter 2 (EAAT2) modulator (Ki=28.7 nM). EAAT2 activator 2 enhances EAAT2-mediated glutamate uptake, improving synaptic glutamate clearance. EAAT2 activator 2 is promising for research of neurodegenerative diseases (e.g., ALS, Alzheimer’s disease) .
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- Formule: C20H22FN3O3
- Masse moléculaire:371.41
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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EAAT2 28.7 nM (Ki) |
Chemical Information
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Masse moléculaire 371.41
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Formule C20H22FN3O3
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SMILES
FCCOC1=CC=C(C=C1)NC(C(N2CCN(CC2)C3=CC=CC=C3)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EAAT2 activator 2 Related Classifications
HY-175296 Related Classifications
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