Fpr2 - formyl peptide receptor 2 Gene

Also Known as Fprl1; Fpr-rs2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 690158

Summary

Enables RAGE receptor binding activity; cargo receptor activity; and scavenger receptor binding activity. Involved in several processes, including cellular response to amyloid-beta; positive regulation of 1-phosphatidylinositol-3-kinase activity; and positive regulation of intracellular signal transduction. Acts upstream of or within negative regulation of neuron apoptotic process. Located in cytoplasm and plasma membrane. Orthologous to human FPR2 (formyl peptide receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Fpr2 Products (1)

mRNA Protein Name
NM_001408783.1 NP_001395712.1 formyl peptide receptor, related sequence 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables RAGE receptor binding IPI
IPI: Inferred from physical interaction
23164356 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

formyl peptide receptor 2-like

formyl peptide receptor, related sequence 2

  • formyl peptide receptor, related sequence 2-like

  • formyl peptide receptor-like 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Nom du produit Effect
Pureté Phase
HY-131180 BMS-986235 99.84% Phase 1
HY-124071 ACT-389949 98.42% Phase 1

Pre-clinical Phase

Bioactive Molecules (21)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P1120 WKYMVm 99.74% Unkown
HY-103286 PD176252 Antagonist 99.38% Unkown
HY-19574 FPR Agonist 43 99.79% Unkown
HY-116216 PD 168368 Antagonist ≥99.0% Unkown
HY-P1744 N-Formyl-Met-Leu-Phe-Lys 99.83% Unkown
HY-P1117 MMK1 99.71% Unkown
HY-W668775 Quin-C7 Antagonist 99.76% Unkown
HY-155335 FPR2 agonist 3 Agonist 99.39% Unkown
HY-144604 FPR2 agonist 2 Agonist 98.51% Unkown
HY-110246 Quin C1 Agonist 98.47% Unkown
HY-P1120A WKYMVm TFA / Unkown
HY-159583 FPR2 agonist 4 Agonist / Unkown
HY-178144 FPR2 agonist 5 / Unkown
HY-181822 BMS-986331 / Unkown
HY-183952 FPR2/ALXR agonist-1 Agonist / Unkown
HY-184654 MR-39 / Unkown
HY-P10432 SHAAGtide Activator / Unkown
HY-P1117A MMK1 TFA / Unkown
HY-RS05086 FPR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16582 Fpr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23016 Fpr2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fpr2 NCBI NCBI:2358