Glycodeoxycholic acid-d5
Based on 1 Customer Validation
Glycodeoxycholic acid-d5 is deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.
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- Formule: C26H38D5NO5
- Masse moléculaire:454.65
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 360-65-6
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Masse moléculaire 454.65
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Formule C26H38D5NO5
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SMILES
[H][C@@]12C([2H])([C@@]([2H])(C([2H])(C[C@@]1([C@H](C3CC2)C[C@H]([C@]4([C@]3(CC[C@@H]4[C@@H](CCC(NCC(O)=O)=O)C)[H])C)O)C)[2H])O)[2H]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvant et solubilité
DMSO : 125 mg/mL (274.94 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Shi C, et al. Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells. Aging (Albany NY). 2020 Aug 3;12(15):15546-15555. [Content Brief]
[3]. Vaz AR, et al. Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid. J Neurochem. 2010 Jan;112(1):56-65. [Content Brief]
[4]. Fauzi A, et al. Role of glycodeoxycholic acid to induce acute pancreatitis in Macaca nemestrina. J Med Primatol. 2022 Jun;51(3):134-142. doi: 10.1111/jmp.12577. Epub 2022 Mar 20. PMID: 35306662; PMCID: PMC9310849. [Content Brief]
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1995 mL | 10.9975 mL | 21.9949 mL | 54.9874 mL |
| 5 mM | 0.4399 mL | 2.1995 mL | 4.3990 mL | 10.9975 mL | |
| 10 mM | 0.2199 mL | 1.0997 mL | 2.1995 mL | 5.4987 mL | |
| 15 mM | 0.1466 mL | 0.7332 mL | 1.4663 mL | 3.6658 mL | |
| 20 mM | 0.1100 mL | 0.5499 mL | 1.0997 mL | 2.7494 mL | |
| 25 mM | 0.0880 mL | 0.4399 mL | 0.8798 mL | 2.1995 mL | |
| 30 mM | 0.0733 mL | 0.3666 mL | 0.7332 mL | 1.8329 mL | |
| 40 mM | 0.0550 mL | 0.2749 mL | 0.5499 mL | 1.3747 mL | |
| 50 mM | 0.0440 mL | 0.2199 mL | 0.4399 mL | 1.0997 mL | |
| 60 mM | 0.0367 mL | 0.1833 mL | 0.3666 mL | 0.9165 mL | |
| 80 mM | 0.0275 mL | 0.1375 mL | 0.2749 mL | 0.6873 mL | |
| 100 mM | 0.0220 mL | 0.1100 mL | 0.2199 mL | 0.5499 mL |
Glycodeoxycholic acid-d5 Related Classifications
HY-W653999 Related Classifications
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