NC 2300
NC 2300 (VEL-0230)is a selective and orally active cysteine cathepsin inhibitor with the IC50 values of 284, 34.5, and 186 nM for cathepsin B, K, and S, respectively.NC 2300 can be used for study of diseases involving bone mineral disorders.
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- CAS No.: 221144-20-3
- Formule: C14H24NNaO5
- Masse moléculaire:309.33
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Chemical Information
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CAS No. 221144-20-3
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Masse moléculaire 309.33
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Formule C14H24NNaO5
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SMILES
CC(C)COC[C@H](CC(C)C)NC([C@@H]1[C@H](O1)C(O[Na])=O)=O
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Synonyms
VEL 0230
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Aoki T,et al. Cathepsin B, K, and S are expressed in cerebral aneurysms and promote the progression of cerebral aneurysms. Stroke. 2008;39(9):2603-2610. [Content Brief]
[2]. Hirai T, et al. Cathepsin K is involved in development of psoriasis-like skin lesions through TLR-dependent Th17 activation [published correction appears in J Immunol. 2014 May 15;192(10):4933]. J Immunol. 2013;190(9):4805-4811. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NC 2300 Related Classifications
HY-15099 Related Classifications
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