Citriniorl A
Citriniorl A is a SIRT1 enhancer with an EC50 of 5.8 μM. Citriniorl A binds to key amino acid residues in the SIRT1 active site to stabilize binding and enhance SIRT1-mediated deacetylation. Citriniorl A can be used for the research of metabolic disorders.
For research use only. We do not sell to patients.
- Formula: C14H14O4
- Molecular Weight:246.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Citriniorl A (compound 1) (varying concentrations; 30 min pre-incubation, 1 h enzymatic reaction at 37°C) exhibits moderate SIRT1 activation activity with an EC50 of 5.8 μM via stable binding to the SIRT1 active site[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 246.26
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Formula C14H14O4
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SMILES
OC1=C(C)C([C@H](C)[C@@H](C)O2)=C(C2=CC(O3)=O)C3=C1
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Structure Classification
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Initial Source
Penicillium citrinum TJ507
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)