D159153
D159153 is a highly selective phosphodiesterase 4 (PDE4) inhibitor. D159153 is promising for research of asthma, chronic obstructive pulmonary disease (COPD), and neuroinflammatory disorders.
For research use only. We do not sell to patients.
- CAS No.: 1158231-00-5
- Formula: C21H18FN3O4
- Molecular Weight:395.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
PDE4 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
<1 nM
Compound: 33; CHEMBLD159153
|
Inhibition of recombinant human PDE4D7 catalytic domain expressed in baculovirus infected sf9 cells using cAMP as substrate
Inhibition of recombinant human PDE4D7 catalytic domain expressed in baculovirus infected sf9 cells using cAMP as substrate
|
[PMID: 26908025] |
Chemical Information
-
CAS No. 1158231-00-5
-
Molecular Weight 395.38
-
Formula C21H18FN3O4
-
SMILES
O=C(N)NC1=CC=C(CC2=CC=C(OC)C(C3=CC=CC([N+]([O-])=O)=C3)=C2F)C=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
D159153 Related Classifications
HY-125251 Related Classifications
Powered by Bioz