D1R antagonist 2
D1R antagonist 2 (Compound 13a) is a BBB-penetrable D1R antagonist with IC50s of 35.6 and 70 nM for cAMP-based D1R and β-arrestin-based D1R, respectively. D1R antagonist 2 effectively antagonizes D1R-mediated cAMP and β-arrestin recruitment. D1R antagonist 2 can be used for neurodegenerative and neuropsychiatric diseases such as schizophrenia, Parkinson’s disease and Alzheimer’s disease research.
For research use only. We do not sell to patients.
- Formula: C21H22BrF2NO4
- Molecular Weight:470.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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D1 Receptor 35.6 ( cAM nM (IC50) |
D1 Receptor 70 (β-arre nM (IC50) |
Chemical Information
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Molecular Weight 470.30
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Formula C21H22BrF2NO4
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SMILES
FC(F)COC1=C(O)C=C([C@H](CC2=C(Br)C=C(O)C(OCC)=C2C3)N3CC4)C4=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
D1R antagonist 2 Related Classifications
HY-178103 Related Classifications
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