DC-S100
DC-S100 is a potent SET7 inhibitor with an IC50 of 30.04 μM. DC-S100 binds to the cofactor (SAM) binding site of SET7 and forms hydrogen bonds and hydrophobic interactions with residues at this site. DC-S100 is applicable to biological studies of epigenetics and related diseases.
For research use only. We do not sell to patients.
- CAS No.: 178803-91-3
- Formula: C15H14N2O5
- Molecular Weight:302.28
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
All Histone Methyltransferase Isoforms
More
Biological Activity
Description
IC50 & Target
[1]|
SETD7/KMT7 30.04 μM (IC50) |
In Vitro
DC-S100 potently inhibits purified SET7 histone methyltransferase activity with an IC50 of 30.04 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
-
CAS No. 178803-91-3
-
Molecular Weight 302.28
-
Formula C15H14N2O5
-
SMILES
O=C(C1=CC=C(C=C1)[N+]([O-])=O)NC2=CC=C(C(OC)=C2)OC
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DC-S100 Related Classifications
HY-125105 Related Classifications
Powered by Bioz