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Cat. No.: HY-146815

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CP19

CP19, a histamine receptor antagonist, is an entry inhibitor against both Ebolavirus (EBOV) and Marburgvirus (MARV) with IC₅₀s of 3.4 μM and 29.5 μM, respectively. CP19 has SI values of 29.4 and 3.4 for EBOV and MARV, respectively. CP19 has antiviral activity.

For research use only. We do not sell to patients.

CAS No.: 1018148-68-9
Formula: C₂₆H₃₀N₂O₅
Molecular Weight:450.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

CP19 Chemical Structure

CAS No.: 1018148-68-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

EBOV

MARV

Histamine Receptor

All Histamine Receptor Isoforms :

All Filovirus Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	CC₅₀	>100 μM Compound: 1; CP19	Cytotoxicity against human A549 cells assessed as reduction in cell viability by Celltiter-Glo assay Cytotoxicity against human A549 cells assessed as reduction in cell viability by Celltiter-Glo assay	[PMID: 32707357]

Chemical Information

CAS No. 1018148-68-9
Molecular Weight 450.53
Formula C₂₆H₃₀N₂O₅
SMILES

O=C1OC2=C(C(C)=C1CC3=CC=CC=C3)C=CC(OCC(CN4CCC(CC4)C(N)=O)O)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yinyi Gao, et al. Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein. Eur J Med Chem. 2020 Oct 15;204:112595. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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CP19

All Histamine Receptor Isoforms

All Filovirus Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CP19 Related Classifications

HY-146815 Related Classifications