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EGFR-IN-189

EGFR-IN-189 (Compound 7) is a selective covalent epidermal growth factor receptor (EGFR) inhibitor with an IC50 of 200 nM. EGFR-IN-189 can effectively inhibit the C797S mutant type of EGFR. EGFR-IN-189 can inhibit cancer cells proliferation and inhibit EGFR phosphorylation and downstream ERK1/2 phosphorylation. EGFR-IN-189 can be used for research of nonsmall cell lung cancer.

For research use only. We do not sell to patients.

  • CAS No.: 3037398-18-5
  • Formula: C26H26N6O
  • Molecular Weight:438.52
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • EGFR-IN-189 Chemical Structure
    EGFR-IN-189 Chemical Structure
CAS No.: 3037398-18-5
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All EGFR Isoforms

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All ERK Isoforms

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100 mg

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  • EGFR-IN-189 Chemical Structure
    EGFR-IN-189 Chemical Structure
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  • EGFR-IN-189