Emzotamig
Based on 1 Customer Validation
Emzotamig is a monoclonal antibody inhibitor targeting tumor necrosis factor (TNF). Emzotamig is promising for research of autoimmune diseases associated with TNF overexpression, such as rheumatoid arthritis and ankylosing spondylitis.
For research use only. We do not sell to patients.
- Purity: 97.35%
- CAS No.: 3037572-57-6
- Molecular Weight:124.59 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
VH-VH-CH1_VL-L-kappa_h-CH2-CH3
Species Reactivity
Human
IC50 & Target
TNFRSF17 & NCR1
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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VH-VH-CH1_VL-L-kappa_h-CH2-CH3
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized BCMA/TNFRSF17 Protein, Human (HEK293, HY-P70827) can bind Emzotamig. The ED50 for this effect is 8.653 ng/mL. -
Immobilized NKp46/NCR1 Protein, Human (HEK293, HY-P77810) can bind Emzotamig. The ED50 for this effect is 172.2 ng/mL.
Chemical Information
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CAS No. 3037572-57-6
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Appearance Liquid
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Molecular Weight 124.59 kDa
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Color Colorless to off-white
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SMILES
N/A
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)