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Cat. No.: HY-120539

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Enofelast

(Synonyms: BI-L-239)

Enofelast (BI-L-239), a 5-lipoxygenase (5-LO) inhibitor, exhibits an IC₅₀ of 2.48 μM for inhibition of calcium ionophore-induced LTB₄ generation.

For research use only. We do not sell to patients.

CAS No.: 125722-16-9
Formula: C₁₆H₁₅FO
Molecular Weight:242.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Enofelast Chemical Structure

CAS No.: 125722-16-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Enofelast (BI-L-239), a 5-lipoxygenase (5-LO) inhibitor, exhibits an IC₅₀ of 2.48 μM for inhibition of calcium ionophore-induced LTB₄ generation^[1].

IC₅₀ & Target

IC50: 2.48 μM (LTB₄)^[1].

All Lipoxygenase Isoforms :

All Leukotriene Receptor Isoforms :

Chemical Information

CAS No. 125722-16-9
Molecular Weight 242.29
Formula C₁₆H₁₅FO
SMILES

OC1=C(C=C(C=C1C)/C=C/C2=CC=C(C=C2)F)C
Synonyms

BI-L-239
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. T C Noonan, et al. Effect of BI-L-239, A-64077 and MK-886 on leukotriene B4 synthesis by chopped guinea pig lung and on antigen-induced tracheal contraction in vitro. Prostaglandins. 1992 Dec;44(6):543-54. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Enofelast

All Lipoxygenase Isoforms

All Leukotriene Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Enofelast Related Classifications

HY-120539 Related Classifications