Enpp-1-IN-31
Enpp-1-IN-31 is a ENPP1 inhibitor with an IC50 of <20 nM (using cGAMP as the substrate). Enpp-1-IN-31 exhibits potential anticancer activity and inhibits the growth and proliferation of mouse colon cancer cells and breast cancer cells.
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- Formel: C18H18BN3O3
- Molecular Weight:335.16
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
Enpp-1-IN-31 (compound 59) inhibits the viability of EMT6, CT26, and MDA-MB-231 cells, with IC50 values of 1-5 μM, <1 μM, and 1-5 μM at 24 h, respectively[1].
Enpp-1-IN-31 exhibits certain metabolic stability, with a residual rate of >70% after incubation with mouse liver S9 fractions for 1 h[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 335.16
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Formel C18H18BN3O3
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SMILES
COC1=C2C(C(N[C@@H](C)C3=CC=C(COB4O)C4=C3)=NC=N2)=CC=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Enpp-1-IN-31 Related Classifications
HY-182772 Related Classifications
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