Ep vinyl quinidine
Ep vinyl quinidine (3-Epiquinine) is an epi-vinyl stereoisomer of Quinidine. Quinidine is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine is also a K+ channel blocker with an IC50 of 19.9 μM. Quinidine can be used for malaria research.
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- No. CAS: 101143-87-7
- Fòrmula: C20H24N2O2
- Peso molecular:324.42
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
Parasite[1]
Chemical Information
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No. CAS 101143-87-7
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Peso molecular 324.42
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Fòrmula C20H24N2O2
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SMILES
O[C@H]([C@]1([H])[N@@]2C[C@H]([C@@H](CC2)C1)C=C)C3=CC=NC4=C3C=C(OC)C=C4
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Synonyms
3-Epiquinine; Epivinylquinidine
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Hu B, et al. Origin of and a Solution for Uneven Efficiency by Cinchona Alkaloid-Derived, Pseudoenantiomeric Catalysts for Asymmetric Reactions. J Am Chem Soc. 2018 Oct 24;140(42):13913-13920. [Content Brief]
[2]. Kehl SJ. Quinidine-induced inhibition of the fast transient outward K+ current in rat melanotrophs. Br J Pharmacol. 1991 Jul;103(3):1807-13. [Content Brief]
[3]. Roden DM, et al. Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide. Pharmacol Ther. 1983;23(2):179-91. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)