1. Cell Cycle/DNA Damage
    Cytoskeleton
    Antibody-drug Conjugate/ADC Related
  2. Microtubule/Tubulin
    ADC Cytotoxin
  3. Fmoc-MMAE

Fmoc-MMAE 

Cat. No.: HY-78933
Handling Instructions

Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC.

For research use only. We do not sell to patients.

Fmoc-MMAE Chemical Structure

Fmoc-MMAE Chemical Structure

CAS No. : 474645-26-6

Size Price Stock Quantity
50 mg USD 200 In-stock
Estimated Time of Arrival: December 31
100 mg USD 340 In-stock
Estimated Time of Arrival: December 31
500 mg USD 1050 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Fmoc-MMAE is a protective group-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Fmoc-MMAE can be used in the synthesis of ADC[1].

IC50 & Target[1]

Auristatin

 

Molecular Weight

940.22

Formula

C₅₄H₇₇N₅O₉

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : ≥ 45 mg/mL (47.86 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0636 mL 5.3179 mL 10.6358 mL
5 mM 0.2127 mL 1.0636 mL 2.1272 mL
10 mM 0.1064 mL 0.5318 mL 1.0636 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Fmoc-MMAE
Cat. No.:
HY-78933
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