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Cat. No.: HY-105196

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DAT-582

DAT-582 is a serotonin 3 (5-HT3) receptor antagonist that has an antiemetic effect.

For research use only. We do not sell to patients.

CAS No.: 141034-42-6
Formula: C₂₂H₂₉Cl₂N₅O
Molecular Weight:450.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

DAT-582 Chemical Structure

CAS No.: 141034-42-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

DAT-582 is a serotonin 3 (5-HT3) receptor antagonist that has an antiemetic effect^[1].

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 141034-42-6
Molecular Weight 450.40
Formula C₂₂H₂₉Cl₂N₅O
SMILES

CC1=CC=CC(CN(CCN(C2)C)C[C@@H]2NC(C3=NNC4=CC=CC=C34)=O)=C1.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yoshida N, et al. DAT-582, a novel serotonin3 receptor antagonist, is a potent and long-lasting antiemetic agent in the ferret and dog. J Pharmacol Exp Ther. 1992 Mar;260(3):1159-65. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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DAT-582

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

DAT-582 Related Classifications

HY-105196 Related Classifications