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Referencia número: HY-117442

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A2B57

A2B57 is a selective inhibitor for SIRT 2 with an IC₅₀ of 6.3 µM.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 1602733-73-2
Fòrmula: C₂₂H₁₉N₅O
Peso molecular:369.42

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

A2B57 Chemical Structure

No. CAS: 1602733-73-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

A2B57 is a selective inhibitor for SIRT 2 with an IC₅₀ of 6.3 µM^[1].

IC₅₀ & Target

SIRT2

6.3 μM (IC₅₀)

Ver todos los productos específicos de isoformas Sirtuin :

Chemical Information

No. CAS 1602733-73-2
Peso molecular 369.42
Fòrmula C₂₂H₁₉N₅O
SMILES

O=C(C1=CC=CC=C1NC2=CC=C(C=C2)C3=CN(N=N3)CC4=CC=CC=C4)N
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Tatum PR, et al., Identification of novel SIRT2-selective inhibitors using a click chemistry approach. Bioorg Med Chem Lett. 2014 Apr 15;24(8):1871-4. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias

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A2B57

Ver todos los productos específicos de isoformas Sirtuin

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

A2B57 Related Classifications

HY-117442 Related Classifications