CC-1069
CC-1069, a structural analog of thalidomide (HY-14658), is a TNF-α inhibitor that inhibits endothelial. CC-1069 can be used to study angiogenesis-dependent tumors such as gliomas.
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- No. CAS: 167887-03-8
- Fòrmula: C19H18N2O5
- Peso molecular:354.36
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas TNF Receptor
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
13 μM
Compound: 3a
|
Inhibition of LPS stimulated Tumor Necrosis Factor-alpha (TNF-alpha) release by human PBMC
Inhibition of LPS stimulated Tumor Necrosis Factor-alpha (TNF-alpha) release by human PBMC
|
[PMID: 9873600] |
| U-937 | IC50 |
9.4 μM
Compound: 3a
|
Inhibition of PDE4 enzyme from U937 cells
Inhibition of PDE4 enzyme from U937 cells
|
[PMID: 9873600] |
Chemical Information
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No. CAS 167887-03-8
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Peso molecular 354.36
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Fòrmula C19H18N2O5
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SMILES
O=C(CC(N1C(C2=C(C1=O)C=CC=C2)=O)C3=CC=C(C(OC)=C3)OC)N
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)