D-Carnitine
Based on 1 publication(s) in Google Scholar
D-Carnitine is an orally available isomer of the essential nutrient L-carnitine that promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation. D-Carnitine has antiparasitic activity.
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- Pureza : 99.94%
- No. CAS: 541-14-0
- Fòrmula: C7H15NO3
- Peso molecular:161.20
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Almacenamiento:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) D-Carnitine
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Actividad biológica
Descripciòn
In Vitro
D-Carnitine (0.5 μM) can inhibit the uptake of L-carnitine by renal brush marginal membrane vesicles in rats[1].
D-Carnitine (0.5, 1 μM) inhibits the uptake of L-carnitine by primary human limbal (HCLE) and conjunctival epithelium (HCjE) cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 541-14-0
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Appearance Solid
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Peso molecular 161.20
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Fòrmula C7H15NO3
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Color Off-white to yellow
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SMILES
O=C(C[C@@H](C[N+](C)(C)C)O)[O-]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvente y solubilidad
In Vitro:
H2O : 175 mg/mL (1085.61 mM; Need ultrasonic)
Ethanol : ≥ 10 mg/mL (62.03 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Stieger B, et al. Characterization of L-carnitine transport by rat kidney brush-border-membrane vesicles. Biochem J. 1995 Jul 15;309 ( Pt 2)(Pt 2):643-7. [Content Brief]
[2]. Xu S, et al. Transport of L-carnitine in human corneal and conjunctival epithelial cells. Mol Vis. 2010 Sep 4;16:1823-31. [Content Brief]
[3]. Manganaro M, et al. Activity of D-carnitine and its derivatives on Trypanosoma infections in rats and mice. Parasite. 2003 Jun;10(2):147-51. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / H2O | 1 mM | 6.2035 mL | 31.0174 mL | 62.0347 mL | 155.0869 mL |
| 5 mM | 1.2407 mL | 6.2035 mL | 12.4069 mL | 31.0174 mL | |
| 10 mM | 0.6203 mL | 3.1017 mL | 6.2035 mL | 15.5087 mL | |
| 15 mM | 0.4136 mL | 2.0678 mL | 4.1356 mL | 10.3391 mL | |
| 20 mM | 0.3102 mL | 1.5509 mL | 3.1017 mL | 7.7543 mL | |
| 25 mM | 0.2481 mL | 1.2407 mL | 2.4814 mL | 6.2035 mL | |
| 30 mM | 0.2068 mL | 1.0339 mL | 2.0678 mL | 5.1696 mL | |
| 40 mM | 0.1551 mL | 0.7754 mL | 1.5509 mL | 3.8772 mL | |
| 50 mM | 0.1241 mL | 0.6203 mL | 1.2407 mL | 3.1017 mL | |
| 60 mM | 0.1034 mL | 0.5170 mL | 1.0339 mL | 2.5848 mL | |
| H2O | 80 mM | 0.0775 mL | 0.3877 mL | 0.7754 mL | 1.9386 mL |
| 100 mM | 0.0620 mL | 0.3102 mL | 0.6203 mL | 1.5509 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-Carnitine Related Classifications
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