DAUDA
Based on 1 Customer Validation
DAUDA is a fluorescent fatty acid analog probe, with Kd values of 0.63 μM, 0.82 μM, and 0.66 μM against subtypes/mutants of Schistosoma mansoni Sm14 fatty acid-binding protein, respectively. DAUDA binds to Sm14 fatty acid-binding protein variants, enters their non-polar binding pockets and alters fluorescence emission properties. DAUDA serves as a tracer in competitive binding assays with natural fatty acids to evaluate the fatty acid-binding capacity of Sm14 protein variants. DAUDA is applicable to the research of schistosomiasis.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.08%
- No. CAS: 73025-02-2
- Fòrmula: C23H34N2O4S
- Peso molecular:434.59
-
Almacenamiento:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Ver todos los productos específicos de isoformas Parasite
More
Actividad biológica
Descripciòn
IC50 & Target
|
Schistosome |
In Vitro
DAUDA (0-4 μM) binds with similar affinity to purified recombinant rSm14-M20, rSm14-T20, and rSm14-A20 proteins, with Kd values of 0.63 μM, 0.82 μM, and 0.66 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 73025-02-2
-
Appearance Solid
-
Peso molecular 434.59
-
Fòrmula C23H34N2O4S
-
Color White to off-white
-
SMILES
O=C(O)CCCCCCCCCCNS(=O)(C1=C2C=CC=C(N(C)C)C2=CC=C1)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (230.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
-
Ficha de datos (275 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3010 mL | 11.5051 mL | 23.0102 mL | 57.5255 mL |
| 5 mM | 0.4602 mL | 2.3010 mL | 4.6020 mL | 11.5051 mL | |
| 10 mM | 0.2301 mL | 1.1505 mL | 2.3010 mL | 5.7525 mL | |
| 15 mM | 0.1534 mL | 0.7670 mL | 1.5340 mL | 3.8350 mL | |
| 20 mM | 0.1151 mL | 0.5753 mL | 1.1505 mL | 2.8763 mL | |
| 25 mM | 0.0920 mL | 0.4602 mL | 0.9204 mL | 2.3010 mL | |
| 30 mM | 0.0767 mL | 0.3835 mL | 0.7670 mL | 1.9175 mL | |
| 40 mM | 0.0575 mL | 0.2876 mL | 0.5753 mL | 1.4381 mL | |
| 50 mM | 0.0460 mL | 0.2301 mL | 0.4602 mL | 1.1505 mL | |
| 60 mM | 0.0384 mL | 0.1918 mL | 0.3835 mL | 0.9588 mL | |
| 80 mM | 0.0288 mL | 0.1438 mL | 0.2876 mL | 0.7191 mL | |
| 100 mM | 0.0230 mL | 0.1151 mL | 0.2301 mL | 0.5753 mL |